Overdue notices: Cutting costs and saving time

Notices NOTICES

This Journal, founded by the Medical Society for the Study of the Venereal Diseases, publishes original work on the investigation and treatment of genitourinary and allied disorders, and review articles, correspondence, and abstracts. ADVICE TO AuTHoRs Paper for publication, which will be accepted on the understanding that they have not been and will not be published elsewhere and are subject t...

Cutting-edge research or cutting-edge artefact? An overdue control experiment complicates the xylem refilling story.

Arguably, the biggest current mystery in water relations research is how embolized xylem vessels refill despite negative pressures in the surrounding transpiration stream (Nardini, Lo Gullo & Salleo 2011). In this issue, Wheeler et al. (2013) set out to investigate the phenomenon in two known refillers, Acer rubrum and Fraxinus americana (Zwieniecki & Holbrook 1998; Zwieniecki et al. 2000). Ins...

Ingredient-specific Particle Sizing: Reducing Risk, Cutting Cost and Saving Time in Preclinical Inhalable Formulation Development

of new drug approval applications submitted to regulatory authorities, pharmaceutical companies are continuing to pursue new delivery methods for their drug products. The inhalation and nasal products had combined sales exceeding US$22 billion in 2007 for treatment of asthma, COPD, allergic rhinitis, influenza, migraine and osteoporosis, and for use in general anaesthesia. 1 One common trend is...

Saving SSD Erase Costs Using WOM Codes

NAND flash, used in modern SSDs, is a write-once medium, where each memory cell must be erased prior to writing. The lifetime of an SSD is limited by the number of erasures allowed on each cell. Thus, minimizing erasures is a key objective in SSD design. A promising approach to eliminate erasures and extend SSD lifetime is to use write-once memory (WOM) codes, designed to accommodate additional...

In Search of Economic Rationality – Puzzles Related to Saving , Voting , and the Opportunity Costs of Time